5n06

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Crystal structure of Tie1 Fibronectin-like domain 3Crystal structure of Tie1 Fibronectin-like domain 3

Structural highlights

5n06 is a 2 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Method:X-ray diffraction, Resolution 2.501Å
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

TIE1_HUMAN Transmembrane tyrosine-protein kinase that may modulate TEK/TIE2 activity and contribute to the regulation of angiogenesis.[1]

See Also

References

  1. ↑ Seegar TC, Eller B, Tzvetkova-Robev D, Kolev MV, Henderson SC, Nikolov DB, Barton WA. Tie1-Tie2 interactions mediate functional differences between angiopoietin ligands. Mol Cell. 2010 Mar 12;37(5):643-55. doi: 10.1016/j.molcel.2010.02.007. PMID:20227369 doi:http://dx.doi.org/10.1016/j.molcel.2010.02.007

5n06, resolution 2.50Å

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OCA
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