5m0t

Alpha-ketoglutarate-dependent non-heme iron oxygenase EasHAlpha-ketoglutarate-dependent non-heme iron oxygenase EasH

Structural highlights 5m0t is a 2 chain structure with sequence from Aspergillus japonicus. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance. Method: X-ray diffraction, Resolution 2.2Å Ligands: , , Resources: FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT Function A0A1L1QK38_ASPJA Publication Abstract from PubMed Aj_EasH is a non-heme iron- and alpha-keto-glutarate-dependent oxidase that is responsible for an unusual cyclopropyl ring formation in the biosynthesis of the fungal ergot alkaloid cycloclavine. The three dimensional structure of Aj_EasH (2.2 A resolution) reported here provides insight into the mechanism of this unusual and complex reaction. Structural characterization of EasH (Aspergillus japonicus) - an oxidase involved in cycloclavine biosynthesis.,Jakubczyk D, Caputi L, Stevenson CE, Lawson DM, O'Connor SE Chem Commun (Camb). 2016 Dec 6;52(99):14306-14309. PMID:27885368 From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.

spinqualitylabelsall models 5m0t, resolution 2.20Å Show:Asymmetric Unit Biological Assembly Drag the structure with the mouse to rotate   Export Animated Image