5lf0

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Human 20S proteasome complex with Epoxomicin at 2.4 AngstromHuman 20S proteasome complex with Epoxomicin at 2.4 Angstrom

Structural highlights

5lf0 is a 24 chain structure with sequence from Homo sapiens and Synthetic construct. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Method:X-ray diffraction, Resolution 2.41Å
Ligands:, , , , , , , ,
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

PSA4_HUMAN The proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. The proteasome has an ATP-dependent proteolytic activity.

See Also

5lf0, resolution 2.41Å

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OCA