5gqh

Cryo-EM structure of PaeCas3-AcrF3 complexCryo-EM structure of PaeCas3-AcrF3 complex

5gqh, resolution 4.20Å Show:Asymmetric Unit Biological Assembly Structural highlights 5gqh is a 3 chain structure with sequence from Pseudomonas aeruginosa UCBPP-PA14 and Pseudomonas phage JBD5. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance. Method: Electron Microscopy, Resolution 4.2Å Experimental data: Check Resources: FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT Function CAS3_PSEAB CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Cas3 plus Cascade participate in CRISPR interference, the third stage of CRISPR immunity (Potential). In this bacteria Y.pestis-subtype CRISPRs do not confer resistance to phage DSM3 or MP22, but instead are required for DMS3-dependent inhibition of biofilm formation and possibly motility. See Also CRISPR subtype I-F Helicase 3D structures