5ej0

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The vaccinia virus H3 envelope protein, a major target of neutralizing antibodies, exhibits a glycosyltransferase fold and binds UDP-GlucoseThe vaccinia virus H3 envelope protein, a major target of neutralizing antibodies, exhibits a glycosyltransferase fold and binds UDP-Glucose

Structural highlights

5ej0 is a 1 chain structure with sequence from Vaccinia virus WR. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Method:X-ray diffraction, Resolution 1.9Å
Ligands:, , , , , , , ,
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

H3_VACCW Envelope protein that binds to heparan sulfate on the cell surface and might provide virion attachment to target cell.[1] [2]

References

  1. Lin CL, Chung CS, Heine HG, Chang W. Vaccinia virus envelope H3L protein binds to cell surface heparan sulfate and is important for intracellular mature virion morphogenesis and virus infection in vitro and in vivo. J Virol. 2000 Apr;74(7):3353-65. PMID:10708453
  2. Gordon J, Kovala T, Dales S. Molecular characterization of a prominent antigen of the vaccinia virus envelope. Virology. 1988 Dec;167(2):361-9. PMID:2462305

5ej0, resolution 1.90Å

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OCA