4mee

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Crystal structure of the transport unit of the autotransporter AIDA-I from Escherichia coliCrystal structure of the transport unit of the autotransporter AIDA-I from Escherichia coli

Structural highlights

4mee is a 1 chain structure with sequence from Escherichia coli. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Method:X-ray diffraction, Resolution 3Å
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

AIDA_ECOLX Potent bacterial adhesin that mediates bacterial attachment to a broad variety of human and other mammalian cells. AIDA possesses additional virulence properties, as it is capable of mediating bacterial autoaggregation via intercellular self-recognition and it is a highly efficient initiator of biofilm formation.[1]

See Also

References

  1. Sherlock O, Schembri MA, Reisner A, Klemm P. Novel roles for the AIDA adhesin from diarrheagenic Escherichia coli: cell aggregation and biofilm formation. J Bacteriol. 2004 Dec;186(23):8058-65. PMID:15547278 doi:http://dx.doi.org/186/23/8058

4mee, resolution 3.00Å

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OCA