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Crystal structure of FGF2-interacting protein from Homo sapiens. Northeast Structural Genomics Consortium Target HR9027A.Crystal structure of FGF2-interacting protein from Homo sapiens. Northeast Structural Genomics Consortium Target HR9027A.
Structural highlights
DiseaseCEP57_HUMAN Mosaic variegated aneuploidy syndrome. The disease is caused by mutations affecting the gene represented in this entry. FunctionCEP57_HUMAN Centrosomal protein which may be required for microtubule attachment to centrosomes. May act by forming ring-like structures around microtubules. Mediates nuclear translocation and mitogenic activity of the internalized growth factor FGF2, but that of FGF1.[1] References
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