4j74

The 1.2A crystal structure of humanized Xenopus MDM2 with RO0503918 - a nutlin fragmentThe 1.2A crystal structure of humanized Xenopus MDM2 with RO0503918 - a nutlin fragment

Structural highlights 4j74 is a 1 chain structure with sequence from Xenopus laevis. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance. Method: X-ray diffraction, Resolution 1.2Å Ligands: , Resources: FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT Function MDM2_XENLA E3 ubiquitin-protein ligase that mediates ubiquitination of p53/TP53, leading to its degration by the proteasome (By similarity). See Also MDM2 3D structures

spinqualitylabelsall models 4j74, resolution 1.20Å Show:Asymmetric Unit Biological Assembly Drag the structure with the mouse to rotate   Export Animated Image