4igl

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Structure of the RHS-repeat containing BC component of the secreted ABC toxin complex from Yersinia entomophagaStructure of the RHS-repeat containing BC component of the secreted ABC toxin complex from Yersinia entomophaga

Structural highlights

4igl is a 4 chain structure with sequence from Yersinia entomophaga. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Method:X-ray diffraction, Resolution 2.49Å
Ligands:,
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

YENB_YERET Part of an orally active toxin complex (TC) with strong insecticidal effects on larvae of the Coleoptera Costelytra zealandica, Acrossidius tasmania and Adoryphorus couloni and some Lepidoptera larvae (PubMed:21278295, PubMed:22158901). The TC has an endochitinase activity (PubMed:21278295) (Probable).[1] [2] [3]

References

  1. Hurst MR, Jones SA, Binglin T, Harper LA, Jackson TA, Glare TR. The main virulence determinant of Yersinia entomophaga MH96 is a broad-host-range toxin complex active against insects. J Bacteriol. 2011 Apr;193(8):1966-80. doi: 10.1128/JB.01044-10. Epub 2011 Jan 28. PMID:21278295 doi:http://dx.doi.org/10.1128/JB.01044-10
  2. Landsberg MJ, Jones SA, Rothnagel R, Busby JN, Marshall SD, Simpson RM, Lott JS, Hankamer B, Hurst MR. 3D structure of the Yersinia entomophaga toxin complex and implications for insecticidal activity. Proc Natl Acad Sci U S A. 2011 Dec 20;108(51):20544-9. doi:, 10.1073/pnas.1111155108. Epub 2011 Dec 7. PMID:22158901 doi:http://dx.doi.org/10.1073/pnas.1111155108
  3. Landsberg MJ, Jones SA, Rothnagel R, Busby JN, Marshall SD, Simpson RM, Lott JS, Hankamer B, Hurst MR. 3D structure of the Yersinia entomophaga toxin complex and implications for insecticidal activity. Proc Natl Acad Sci U S A. 2011 Dec 20;108(51):20544-9. doi:, 10.1073/pnas.1111155108. Epub 2011 Dec 7. PMID:22158901 doi:http://dx.doi.org/10.1073/pnas.1111155108

4igl, resolution 2.49Å

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OCA