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Mre11 ATLD17/18 mutation retains Tel1/ATM activity but blocks DNA double-strand break repairMre11 ATLD17/18 mutation retains Tel1/ATM activity but blocks DNA double-strand break repair
Structural highlights
FunctionMRE11_PYRFU Involved in DNA double-strand break repair (DSBR). The Rad50/Mre11 complex possesses single-strand endonuclease activity and ATP-dependent double-strand-specific 3'-5' exonuclease activity. |
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