4hd0

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Mre11 ATLD17/18 mutation retains Tel1/ATM activity but blocks DNA double-strand break repairMre11 ATLD17/18 mutation retains Tel1/ATM activity but blocks DNA double-strand break repair

Structural highlights

4hd0 is a 2 chain structure with sequence from Pyrococcus furiosus DSM 3638. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Method:X-ray diffraction, Resolution 2.3Å
Ligands:
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

MRE11_PYRFU Involved in DNA double-strand break repair (DSBR). The Rad50/Mre11 complex possesses single-strand endonuclease activity and ATP-dependent double-strand-specific 3'-5' exonuclease activity.

4hd0, resolution 2.30Å

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OCA