4h0n

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Crystal structure of Spodoptera frugiperda DNMT2 E260A/E261A/K263A mutantCrystal structure of Spodoptera frugiperda DNMT2 E260A/E261A/K263A mutant

Structural highlights

4h0n is a 4 chain structure with sequence from Spodoptera frugiperda. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Method:X-ray diffraction, Resolution 2.712Å
Ligands:,
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

TRDMT_SPOFR Specifically methylates cytosine 38 in the anticodon loop of tRNA(Asp) (By similarity). Also has DNA (cytosine-5)-methyltransferase activity (PubMed:23103599). Shows affinity for both tRNA(Asp) and DNA substrates (PubMed:23103599).[UniProtKB:O14717][1]

See Also

References

  1. ↑ Li S, Du J, Yang H, Yin J, Ding J, Zhong J. Functional and structural characterization of DNMT2 from Spodoptera frugiperda. J Mol Cell Biol. 2013 Feb;5(1):64-6. doi: 10.1093/jmcb/mjs057. Epub 2012 Oct 25. PMID:23103599 doi:http://dx.doi.org/10.1093/jmcb/mjs057

4h0n, resolution 2.71Å

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OCA
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