4goe

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Crystal structure of the SGTA homodimerization domain with a covalent modification of a single C38Crystal structure of the SGTA homodimerization domain with a covalent modification of a single C38

Structural highlights

4goe is a 2 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Method:X-ray diffraction, Resolution 1.45Å
Ligands:,
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

SGTA_HUMAN Co-chaperone that binds directly to HSC70 and HSP70 and regulates their ATPase activity.[1]

See Also

References

  1. Dutta S, Tan YJ. Structural and functional characterization of human SGT and its interaction with Vpu of the human immunodeficiency virus type 1. Biochemistry. 2008 Sep 23;47(38):10123-31. Epub 2008 Aug 30. PMID:18759457 doi:http://dx.doi.org/10.1021/bi800758a

4goe, resolution 1.45Å

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OCA