4elb

Structure-activity relationship guides enantiomeric preference among potent inhibitors of B. anthracis dihydrofolate reductaseStructure-activity relationship guides enantiomeric preference among potent inhibitors of B. anthracis dihydrofolate reductase

Structural highlights 4elb is a 8 chain structure with sequence from Bacillus anthracis str. Sterne. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance. Method: X-ray diffraction, Resolution 2.6Å Ligands: , , , Resources: FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT Function Q81R22_BACAN Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis (By similarity).[PIRNR:PIRNR000194] See Also Dihydrofolate reductase 3D structures

spinqualitylabelsall models 4elb, resolution 2.60Å Show:Asymmetric Unit Biological Assembly Drag the structure with the mouse to rotate   Export Animated Image