4eil

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Crystal Structure of the loop truncated Toxoplasma gondii TS-DHFRCrystal Structure of the loop truncated Toxoplasma gondii TS-DHFR

Structural highlights

4eil is a 8 chain structure with sequence from Toxoplasma gondii. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Method:X-ray diffraction, Resolution 2.1971Å
Ligands:, , ,
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

DRTS_TOXGO Bifunctional enzyme. Involved in de novo dTMP biosynthesis. Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, DNA precursor synthesis, and for the conversion of dUMP to dTMP (By similarity).

See Also

4eil, resolution 2.20Å

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OCA