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Crystal Structure of the loop truncated Toxoplasma gondii TS-DHFRCrystal Structure of the loop truncated Toxoplasma gondii TS-DHFR
Structural highlights
FunctionDRTS_TOXGO Bifunctional enzyme. Involved in de novo dTMP biosynthesis. Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, DNA precursor synthesis, and for the conversion of dUMP to dTMP (By similarity). See Also |
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