3vqf

Crystal Structure Analysis of the PDZ Domain Derived from the Tight Junction Regulating ProteinCrystal Structure Analysis of the PDZ Domain Derived from the Tight Junction Regulating Protein

Structural highlights 3vqf is a 1 chain structure with sequence from Mus musculus. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance. Method: X-ray diffraction, Resolution 1.199Å Resources: FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT Function LNX1_MOUSE E3 ubiquitin-protein ligase that mediates ubiquitination and subsequent proteasomal degradation of NUMB. E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates. Mediates ubiquitination of isoform p66 and isoform p72 of NUMB, but not that of isoform p71 or isoform p65. Isoform 2 provides an endocytic scaffold for IGSF5/JAM4. See Also Ubiquitin protein ligase 3D structures

spinqualitylabelsall models 3vqf, resolution 1.20Å Show:Asymmetric Unit Biological Assembly Drag the structure with the mouse to rotate   Export Animated Image