3v92

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S663A Stable-5-LOXS663A Stable-5-LOX

Structural highlights

3v92 is a 2 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Method:X-ray diffraction, Resolution 2.74Å
Ligands:
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

LOX5_HUMAN Catalyzes the first step in leukotriene biosynthesis, and thereby plays a role in inflammatory processes.[1]

References

  1. ↑ Gilbert NC, Bartlett SG, Waight MT, Neau DB, Boeglin WE, Brash AR, Newcomer ME. The structure of human 5-lipoxygenase. Science. 2011 Jan 14;331(6014):217-9. PMID:21233389 doi:10.1126/science.1197203

3v92, resolution 2.74Å

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OCA
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