3u0x

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Crystal structure of the B-specific-1,3-galactosyltransferase (GTB) in complex with compound 382Crystal structure of the B-specific-1,3-galactosyltransferase (GTB) in complex with compound 382

Structural highlights

3u0x is a 2 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Method:X-ray diffraction, Resolution 1.85Å
Ligands:, , ,
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

BGAT_HUMAN This protein is the basis of the ABO blood group system. The histo-blood group ABO involves three carbohydrate antigens: A, B, and H. A, B, and AB individuals express a glycosyltransferase activity that converts the H antigen to the A antigen (by addition of UDP-GalNAc) or to the B antigen (by addition of UDP-Gal), whereas O individuals lack such activity.

See Also

3u0x, resolution 1.85Å

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OCA