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Cytochrome P450 2B4 mutant L437A in complex with 4-(4-chlorophenyl)imidazoleCytochrome P450 2B4 mutant L437A in complex with 4-(4-chlorophenyl)imidazole
Structural highlights
FunctionCP2B4_RABIT Cytochromes P450 are a group of heme-thiolate monooxygenases. In liver microsomes, this enzyme is involved in an NADPH-dependent electron transport pathway. It oxidizes a variety of structurally unrelated compounds, including steroids, fatty acids, and xenobiotics. In the epoxidation of arachidonic acid it has a unique preference for the 5,6-olefin. See Also |
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