3sie

Crystal structure of the PDE5A1 catalytic domain in complex with novel inhibitorsCrystal structure of the PDE5A1 catalytic domain in complex with novel inhibitors

Structural highlights

3sie is a 2 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Method:	X-ray diffraction, Resolution 1.93Å
Ligands:
Resources:	FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

PDE5A_HUMAN Plays a role in signal transduction by regulating the intracellular concentration of cyclic nucleotides. This phosphodiesterase catalyzes the specific hydrolysis of cGMP to 5'-GMP.

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3sie

Crystal structure of the PDE5A1 catalytic domain in complex with novel inhibitorsCrystal structure of the PDE5A1 catalytic domain in complex with novel inhibitors

Structural highlights

Function

See Also

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3sie

Crystal structure of the PDE5A1 catalytic domain in complex with novel inhibitorsCrystal structure of the PDE5A1 catalytic domain in complex with novel inhibitors

Structural highlights

Function

See Also

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