3sai

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Bacuills anthracis Dihydrofolate Reductase bound to propargyl-linked TMP analog, UCP1015Bacuills anthracis Dihydrofolate Reductase bound to propargyl-linked TMP analog, UCP1015

Structural highlights

3sai is a 2 chain structure with sequence from Bacillus anthracis. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Method:X-ray diffraction, Resolution 2.25Å
Ligands:, , ,
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

Q81R22_BACAN Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis (By similarity).[PIRNR:PIRNR000194]

See Also

3sai, resolution 2.25Å

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OCA