3rvq

Structure of the CheY-Mn2+ Complex with substitutions at 59 and 89: N59D E89KStructure of the CheY-Mn2+ Complex with substitutions at 59 and 89: N59D E89K

Structural highlights

3rvq is a 1 chain structure with sequence from Escherichia coli K-12. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Method:	X-ray diffraction, Resolution 1.15Å
Ligands:
Resources:	FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

CHEY_ECOLI Involved in the transmission of sensory signals from the chemoreceptors to the flagellar motors. In its active (phosphorylated or acetylated) form, CheY exhibits enhanced binding to a switch component, FliM, at the flagellar motor which induces a change from counterclockwise to clockwise flagellar rotation. Overexpression of CheY in association with MotA and MotB improves motility of a ycgR disruption, suggesting there is an interaction (direct or indirect) between the c-di-GMP-binding flagellar brake protein and the flagellar stator.^[1]

References

↑ Paul K, Nieto V, Carlquist WC, Blair DF, Harshey RM. The c-di-GMP binding protein YcgR controls flagellar motor direction and speed to affect chemotaxis by a "backstop brake" mechanism. Mol Cell. 2010 Apr 9;38(1):128-39. doi: 10.1016/j.molcel.2010.03.001. Epub 2010, Mar 25. PMID:20346719 doi:10.1016/j.molcel.2010.03.001

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OCA

[1] Paul K, Nieto V, Carlquist WC, Blair DF, Harshey RM. The c-di-GMP binding protein YcgR controls flagellar motor direction and speed to affect chemotaxis by a "backstop brake" mechanism. Mol Cell. 2010 Apr 9;38(1):128-39. doi: 10.1016/j.molcel.2010.03.001. Epub 2010, Mar 25. PMID:20346719 doi:10.1016/j.molcel.2010.03.001

[1]

3rvq

Structure of the CheY-Mn2+ Complex with substitutions at 59 and 89: N59D E89KStructure of the CheY-Mn2+ Complex with substitutions at 59 and 89: N59D E89K

Structural highlights

Function

See Also

References

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3rvq

Structure of the CheY-Mn2+ Complex with substitutions at 59 and 89: N59D E89KStructure of the CheY-Mn2+ Complex with substitutions at 59 and 89: N59D E89K

Structural highlights

Function

See Also

References

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