3rko

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Crystal structure of the membrane domain of respiratory complex I from E. coli at 3.0 angstrom resolutionCrystal structure of the membrane domain of respiratory complex I from E. coli at 3.0 angstrom resolution

Structural highlights

3rko is a 12 chain structure with sequence from Escherichia coli BL21(DE3). The December 2011 RCSB PDB Molecule of the Month feature on Complex I by David Goodsell is 10.2210/rcsb_pdb/mom_2011_12. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Method:X-ray diffraction, Resolution 3Å
Ligands:,
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

NUOK_ECOBD NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.[HAMAP-Rule:MF_01456]

See Also

3rko, resolution 3.00Å

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OCA