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Crystal structure of the M. tuberculosis beta clampCrystal structure of the M. tuberculosis beta clamp
Structural highlights
FunctionDPO3B_MYCTU DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The beta chain is required for initiation of replication once it is clamped onto DNA, it slides freely (bidirectional and ATP-independent) along duplex DNA (By similarity). See Also |
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