3qr7

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Crystal structure of the C-terminal fragment of the bacteriophage P2 membrane-piercing protein gpVCrystal structure of the C-terminal fragment of the bacteriophage P2 membrane-piercing protein gpV

Structural highlights

3qr7 is a 2 chain structure with sequence from Escherichia virus P2. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Method:X-ray diffraction, Resolution 0.94Å
Ligands:, , ,
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

SPIKE_BPP2 Forms the small spikes on the baseplate that plug the end of the tube before DNA ejection and form a channel perforating the host membrane during ejection. Involved in baseplate assembly.[1] [2]

References

  1. Yamashita E, Nakagawa A, Takahashi J, Tsunoda K, Yamada S, Takeda S. The host-binding domain of the P2 phage tail spike reveals a trimeric iron-binding structure. Acta Crystallogr Sect F Struct Biol Cryst Commun. 2011 Aug 1;67(Pt 8):837-41., Epub 2011 Jul 13. PMID:21821878 doi:10.1107/S1744309111005999
  2. Browning C, Shneider MM, Bowman VD, Schwarzer D, Leiman PG. Phage pierces the host cell membrane with the iron-loaded spike. Structure. 2012 Feb 8;20(2):326-39. PMID:22325780 doi:10.1016/j.str.2011.12.009

3qr7, resolution 0.94Å

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OCA