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Structure of a Bacterial Ribonuclease P Holoenzyme in Complex with tRNAStructure of a Bacterial Ribonuclease P Holoenzyme in Complex with tRNA
Structural highlights
FunctionRNPA_THEMA RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme (By similarity). See Also |
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