3pdv

Structure of the PDlim2 PDZ domain in complex with the C-terminal 6-peptide extension of NS1Structure of the PDlim2 PDZ domain in complex with the C-terminal 6-peptide extension of NS1

Structural highlights

3pdv is a 1 chain structure with sequence from Homo sapiens and Influenza A virus (A/chicken/Henan/12/2004(H5N1)). Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Method:	X-ray diffraction, Resolution 2.2Å
Ligands:
Resources:	FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

PDLI2_HUMAN Probable adapter protein located at the actin cytoskeleton that promotes cell attachment. Necessary for the migratory capacity of epithelial cells. Overexpression enhances cell adhesion to collagen and fibronectin and suppresses anchorage independent growth. May contribute to tumor cell migratory capacity.

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OCA

3pdv

Structure of the PDlim2 PDZ domain in complex with the C-terminal 6-peptide extension of NS1Structure of the PDlim2 PDZ domain in complex with the C-terminal 6-peptide extension of NS1

Structural highlights

Function

See Also

Contents

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