3p45
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Crystal structure of apo-caspase-6 at physiological pHCrystal structure of apo-caspase-6 at physiological pH
Structural highlights
FunctionCASP6_HUMAN Involved in the activation cascade of caspases responsible for apoptosis execution. Cleaves poly(ADP-ribose) polymerase in vitro, as well as lamins. Overexpression promotes programmed cell death. See Also |
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