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Crystal Structure of Cell Division Cycle 25C Protein Isoform A from Homo sapiensCrystal Structure of Cell Division Cycle 25C Protein Isoform A from Homo sapiens
Structural highlights
FunctionMPIP3_HUMAN Functions as a dosage-dependent inducer in mitotic control. Tyrosine protein phosphatase required for progression of the cell cycle. When phosphorylated, highly effective in activating G2 cells into prophase. Directly dephosphorylates CDK1 and activates its kinase activity.[1] Evolutionary Conservation![]() Check, as determined by ConSurfDB. You may read the explanation of the method and the full data available from ConSurf. See AlsoReferences
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