3o70

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PHD-type zinc finger of human PHD finger protein 13PHD-type zinc finger of human PHD finger protein 13

Structural highlights

3o70 is a 1 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Method:X-ray diffraction, Resolution 1.85Å
Ligands:,
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

PHF13_HUMAN Modulates chromatin structure. Required for normal chromosome condensation during the early stages of mitosis. Required for normal chromosome separation during mitosis.[1]

Evolutionary Conservation

Check, as determined by ConSurfDB. You may read the explanation of the method and the full data available from ConSurf.

References

  1. ↑ Kinkley S, Staege H, Mohrmann G, Rohaly G, Schaub T, Kremmer E, Winterpacht A, Will H. SPOC1: a novel PHD-containing protein modulating chromatin structure and mitotic chromosome condensation. J Cell Sci. 2009 Aug 15;122(Pt 16):2946-56. doi: 10.1242/jcs.047365. Epub 2009, Jul 28. PMID:19638409 doi:10.1242/jcs.047365

3o70, resolution 1.85Å

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OCA
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