3mc6

Crystal structure of ScDPL1Crystal structure of ScDPL1

3mc6 is a 2 chain structure with sequence from Saccharomyces cerevisiae. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Method:	X-ray diffraction, Resolution 3.15Å
Ligands:	,
Resources:	FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

SGPL_YEAST Cleaves phosphorylated sphingoid bases (PSBs), such as sphingosine-1-phosphate, into fatty aldehydes and phosphoethanolamine.^[1] ^[2]

Check, as determined by ConSurfDB. You may read the explanation of the method and the full data available from ConSurf.

↑ Bourquin F, Riezman H, Capitani G, Grutter MG. Structure and function of sphingosine-1-phosphate lyase, a key enzyme of sphingolipid metabolism. Structure. 2010 Aug 11;18(8):1054-65. PMID:20696404 doi:10.1016/j.str.2010.05.011
↑ Saba JD, Nara F, Bielawska A, Garrett S, Hannun YA. The BST1 gene of Saccharomyces cerevisiae is the sphingosine-1-phosphate lyase. J Biol Chem. 1997 Oct 17;272(42):26087-90. PMID:9334171