3hzz

2.4 Angstrom Crystal Structure of Streptomyces collinus crotonyl CoA carboxylase/reductase2.4 Angstrom Crystal Structure of Streptomyces collinus crotonyl CoA carboxylase/reductase

Structural highlights

3hzz is a 4 chain structure with sequence from Streptomyces collinus. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Method:	X-ray diffraction, Resolution 2.4Å
Ligands:
Resources:	FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

CCR_STRCU May play a role in supplying butyryl-CoA for straight-chain fatty acid biosynthesis. Catalyzes the conversion of crotonyl-CoA to butyryl-CoA. It shows a high substrate specificity for crotonyl-CoA, a short-chain-length (C4), but no measurable activity is observed with shorter (C3) or longer-chain-length enoyl-CoA thioesters.^[1]

Evolutionary Conservation

Check, as determined by ConSurfDB. You may read the explanation of the method and the full data available from ConSurf.

References

↑ Wallace KK, Bao ZY, Dai H, Digate R, Schuler G, Speedie MK, Reynolds KA. Purification of crotonyl-CoA reductase from Streptomyces collinus and cloning, sequencing and expression of the corresponding gene in Escherichia coli. Eur J Biochem. 1995 Nov 1;233(3):954-62. PMID:8521864 doi:10.1111/j.1432-1033.1995.954_3.x

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OCA

[1] Wallace KK, Bao ZY, Dai H, Digate R, Schuler G, Speedie MK, Reynolds KA. Purification of crotonyl-CoA reductase from Streptomyces collinus and cloning, sequencing and expression of the corresponding gene in Escherichia coli. Eur J Biochem. 1995 Nov 1;233(3):954-62. PMID:8521864 doi:10.1111/j.1432-1033.1995.954_3.x

[1]

3hzz

2.4 Angstrom Crystal Structure of Streptomyces collinus crotonyl CoA carboxylase/reductase2.4 Angstrom Crystal Structure of Streptomyces collinus crotonyl CoA carboxylase/reductase

Structural highlights

Function

Evolutionary Conservation

References

Contents

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3hzz

2.4 Angstrom Crystal Structure of Streptomyces collinus crotonyl CoA carboxylase/reductase2.4 Angstrom Crystal Structure of Streptomyces collinus crotonyl CoA carboxylase/reductase

Structural highlights

Function

Evolutionary Conservation

References

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