3fwr

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Crystal Structure of the CBS domains from the Bacillus subtilis CcpN repressor complexed with ADPCrystal Structure of the CBS domains from the Bacillus subtilis CcpN repressor complexed with ADP

Structural highlights

3fwr is a 2 chain structure with sequence from Bacillus subtilis. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Method:X-ray diffraction, Resolution 2.45Å
Ligands:
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

CCPN_BACSU Transcription repressor that binds to the promoter of gapB and pckA genes, preventing their expression. Acts as a regulator for catabolite repression of gluconeogenic genes.[1]

Evolutionary Conservation

Check, as determined by ConSurfDB. You may read the explanation of the method and the full data available from ConSurf.

References

  1. Servant P, Le Coq D, Aymerich S. CcpN (YqzB), a novel regulator for CcpA-independent catabolite repression of Bacillus subtilis gluconeogenic genes. Mol Microbiol. 2005 Mar;55(5):1435-51. PMID:15720552 doi:http://dx.doi.org/10.1111/j.1365-2958.2005.04473.x

3fwr, resolution 2.45Å

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OCA