3e26

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Crystal structure of M. tuberculosis glucosyl-3-phosphoglycerate synthaseCrystal structure of M. tuberculosis glucosyl-3-phosphoglycerate synthase

Structural highlights

3e26 is a 1 chain structure with sequence from Mycobacterium tuberculosis. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Method:X-ray diffraction, Resolution 2.5Å
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

GPGS_MYCTU Involved in the biosynthesis of methylglucose lipopolysaccharides (MGLPs). Catalyzes the condensation of NDP-glucose and 3-phospho-glycerate (3-PGA) to yield glucosyl-3-phosphoglycerate (GPG).[1]

Evolutionary Conservation

Check, as determined by ConSurfDB. You may read the explanation of the method and the full data available from ConSurf.

See Also

References

  1. Urresti S, Albesa-Jove D, Schaeffer F, Pham HT, Kaur D, Gest P, van der Woerd MJ, Carreras-Gonzalez A, Lopez-Fernandez S, Alzari PM, Brennan PJ, Jackson M, Guerin ME. Mechanistic insights into the retaining glucosyl-3-phosphoglycerate synthase from mycobacteria. J Biol Chem. 2012 May 25. PMID:22637481 doi:10.1074/jbc.M112.368191

3e26, resolution 2.50Å

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OCA