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Crystal structure of Actin capping protein in complex with CARMIL fragmentCrystal structure of Actin capping protein in complex with CARMIL fragment
Structural highlights
FunctionCAZA1_CHICK F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments. CapZ may mediate the attachment of the barbed ends of actin filaments to the Z-line. See Also |
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