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Structure of the 6-4 photolyase of D. melanogaster in complex with the non-natural N4-methyl T(6-4)C lesionStructure of the 6-4 photolyase of D. melanogaster in complex with the non-natural N4-methyl T(6-4)C lesion
Structural highlights
FunctionEvolutionary Conservation![]() Check, as determined by ConSurfDB. You may read the explanation of the method and the full data available from ConSurf. Publication Abstract from PubMedRepair of the Dewar valence isomers by (6-4) photolyases proceeds via an enzyme catalyzed ring-opening reaction of the Dewar lesion to the (6-4) photoproduct. DNA (6-4) Photolyases Reduce Dewar Isomers for Isomerization into (6-4) Lesions.,Glas AF, Kaya E, Schneider S, Heil K, Fazio D, Maul MJ, Carell T J Am Chem Soc. 2010 Feb 18. PMID:20166732[1] From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine. References
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