2wb6

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Crystal structure of AFV1-102, a protein from the Acidianus Filamentous Virus 1Crystal structure of AFV1-102, a protein from the Acidianus Filamentous Virus 1

Structural highlights

2wb6 is a 1 chain structure with sequence from Acidianus filamentous virus 1. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Method:X-ray diffraction, Resolution 1.95Å
Ligands:
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

Y102_AFV1Y

Publication Abstract from PubMed

Viruses infecting hyperthermophilic archaea have intriguing morphologies and genomic properties. The vast majority of their genes do not have homologs other than in other hyperthermophilic viruses, and the biology of these viruses is poorly understood. As part of a structural genomics project on the proteins of these viruses, we present here the structure of a 102 amino acid protein from acidianus filamentous virus 1 (AFV1-102). The structure shows that it is made of two identical motifs that have poor sequence similarity. Although no function can be proposed from structural analysis, tight binding of the gateway tag peptide in a groove between the two motifs suggests AFV1-102 is involved in protein protein interactions.

Crystal structure of AFV1-102, a protein from the acidianus filamentous virus 1.,Keller J, Leulliot N, Collinet B, Campanacci V, Cambillau C, Pranghisvilli D, van Tilbeurgh H Protein Sci. 2009 Apr;18(4):845-9. PMID:19319936[1]

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.

References

  1. Keller J, Leulliot N, Collinet B, Campanacci V, Cambillau C, Pranghisvilli D, van Tilbeurgh H. Crystal structure of AFV1-102, a protein from the acidianus filamentous virus 1. Protein Sci. 2009 Apr;18(4):845-9. PMID:19319936 doi:10.1002/pro.79

2wb6, resolution 1.95Å

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