2v40

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Human Adenylosuccinate synthetase isozyme 2 in complex with GDPHuman Adenylosuccinate synthetase isozyme 2 in complex with GDP

Structural highlights

2v40 is a 1 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Method:X-ray diffraction, Resolution 1.9Å
Ligands:
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

PURA2_HUMAN Plays an important role in the de novo pathway and in the salvage pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP.[UniProtKB:P46664]

Evolutionary Conservation

Check, as determined by ConSurfDB. You may read the explanation of the method and the full data available from ConSurf.

See Also

2v40, resolution 1.90Å

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OCA