2qme

Crystal structure of human RAC3 in complex with CRIB domain of human p21-activated kinase 1 (PAK1)Crystal structure of human RAC3 in complex with CRIB domain of human p21-activated kinase 1 (PAK1)

Structural highlights 2qme is a 2 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance. Method: X-ray diffraction, Resolution 1.75Å Ligands: , , Resources: FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT Function RAC3_HUMAN Plasma membrane-associated small GTPase which cycles between an active GTP-bound and inactive GDP-bound state. In active state binds to a variety of effector proteins to regulate cellular responses, such as cell spreading and the formation of actin-based protusions including lamellipodia and membrane ruffles. Evolutionary Conservation Check, as determined by ConSurfDB. You may read the explanation of the method and the full data available from ConSurf. See Also Rac 3D structures Serine/threonine protein kinase 3D structures

spinqualitylabelsall models 2qme, resolution 1.75Å Show:Asymmetric Unit Biological Assembly Drag the structure with the mouse to rotate   Export Animated Image