2q80

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Crystal structure of human geranylgeranyl pyrophosphate synthase bound to GGPPCrystal structure of human geranylgeranyl pyrophosphate synthase bound to GGPP

Structural highlights

2q80 is a 6 chain structure with sequence from Homo sapiens. This structure supersedes the now removed PDB entry 2fvi. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Method:X-ray diffraction, Resolution 2.7Å
Ligands:,
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

GGPPS_HUMAN Catalyzes the trans-addition of the three molecules of IPP onto DMAPP to form geranylgeranyl pyrophosphate, an important precursor of carotenoids and geranylated proteins.

Evolutionary Conservation

Check, as determined by ConSurfDB. You may read the explanation of the method and the full data available from ConSurf.

See Also

2q80, resolution 2.70Å

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OCA