2nch

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Solution structure of translation initiation factor IF1 from wolbachia endosymbiont strain TRS of Brugia malayiSolution structure of translation initiation factor IF1 from wolbachia endosymbiont strain TRS of Brugia malayi

Structural highlights

2nch is a 1 chain structure with sequence from Wolbachia endosymbiont strain TRS of Brugia malayi. Full experimental information is available from OCA. For a guided tour on the structure components use FirstGlance.
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

Q5GT92_WOLTR One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex.[HAMAP-Rule:MF_00075][SAAS:SAAS00571772]

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OCA