Structural highlights
Function
TX31A_SCOMU This toxin inhibits voltage-gated potassium channel currents in DRG neurons (IC(50)=44.2 nM). In vivo, insects injected with this toxin showed signs of neurotoxicity including twitching, paralysis, and body contraction.[1]
References
- ↑ Yang S, Liu Z, Xiao Y, Li Y, Rong M, Liang S, Zhang Z, Yu H, King GF, Lai R. Chemical punch packed in venoms makes centipedes excellent predators. Mol Cell Proteomics. 2012 Sep;11(9):640-50. PMID:22595790 doi:10.1074/mcp.M112.018853