2lw3

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Solution structure of the soluble domain of MmpS4 from Mycobacterium tuberculosisSolution structure of the soluble domain of MmpS4 from Mycobacterium tuberculosis

Structural highlights

2lw3 is a 1 chain structure with sequence from Mycobacterium tuberculosis. Full experimental information is available from OCA. For a guided tour on the structure components use FirstGlance.
Method:Solution NMR
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

MMPS4_MYCTU Part of an export system, which is required for biosynthesis and secretion of siderophores. Essential for virulence.[1]

References

  1. ↑ Wells RM, Jones CM, Xi Z, Speer A, Danilchanka O, Doornbos KS, Sun P, Wu F, Tian C, Niederweis M. Discovery of a Siderophore Export System Essential for Virulence of Mycobacterium tuberculosis. PLoS Pathog. 2013 Jan;9(1):e1003120. doi: 10.1371/journal.ppat.1003120. Epub 2013, Jan 31. PMID:23431276 doi:http://dx.doi.org/10.1371/journal.ppat.1003120
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OCA
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