2ljp

Backbone 1H, 13C, and 15N Chemical Shift Assignments for E.coli Ribonuclease P proteinBackbone 1H, 13C, and 15N Chemical Shift Assignments for E.coli Ribonuclease P protein

Structural highlights

2ljp is a 1 chain structure with sequence from Escherichia coli K-12. Full experimental information is available from OCA. For a guided tour on the structure components use FirstGlance.
Method:	Solution NMR
Resources:	FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

RNPA_ECOLI RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme.[HAMAP-Rule:MF_00227]^[1]

References

↑ Chen WY, Singh D, Lai LB, Stiffler MA, Lai HD, Foster MP, Gopalan V. Fidelity of tRNA 5'-maturation: a possible basis for the functional dependence of archaeal and eukaryal RNase P on multiple protein cofactors. Nucleic Acids Res. 2012 May;40(10):4666-80. doi: 10.1093/nar/gks013. Epub 2012, Jan 31. PMID:22298511 doi:http://dx.doi.org/10.1093/nar/gks013

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OCA

[1] Chen WY, Singh D, Lai LB, Stiffler MA, Lai HD, Foster MP, Gopalan V. Fidelity of tRNA 5'-maturation: a possible basis for the functional dependence of archaeal and eukaryal RNase P on multiple protein cofactors. Nucleic Acids Res. 2012 May;40(10):4666-80. doi: 10.1093/nar/gks013. Epub 2012, Jan 31. PMID:22298511 doi:http://dx.doi.org/10.1093/nar/gks013

[1]

2ljp

Backbone 1H, 13C, and 15N Chemical Shift Assignments for E.coli Ribonuclease P proteinBackbone 1H, 13C, and 15N Chemical Shift Assignments for E.coli Ribonuclease P protein

Structural highlights

Function

See Also

References

Contents

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2ljp

Backbone 1H, 13C, and 15N Chemical Shift Assignments for E.coli Ribonuclease P proteinBackbone 1H, 13C, and 15N Chemical Shift Assignments for E.coli Ribonuclease P protein

Structural highlights

Function

See Also

References

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