2l04

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The Solution Structure of the C-terminal Ig-like Domain of the Bacteriophage Lambda Tail Tube ProteinThe Solution Structure of the C-terminal Ig-like Domain of the Bacteriophage Lambda Tail Tube Protein

Structural highlights

2l04 is a 1 chain structure with sequence from Escherichia virus Lambda. Full experimental information is available from OCA. For a guided tour on the structure components use FirstGlance.
Method:Solution NMR
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

TUBE_LAMBD Forms the phage's tail tube composed of 32 hexameric disks. When it encounters the appropriate initiation complex gpM and gpL, it assembles in hexameric rings that stack on top of each others. Multimerization ceases when the correct tail length is achieved through a mechanism dependent on tail terminator protein.[1] [2]

Evolutionary Conservation

Check, as determined by ConSurfDB. You may read the explanation of the method and the full data available from ConSurf.

References

  1. Katsura I. Mechanism of length determination in bacteriophage lambda tails. Adv Biophys. 1990;26:1-18. doi: 10.1016/0065-227x(90)90004-d. PMID:2150582 doi:http://dx.doi.org/10.1016/0065-227x(90)90004-d
  2. Xu J, Hendrix RW, Duda RL. Chaperone-protein interactions that mediate assembly of the bacteriophage lambda tail to the correct length. J Mol Biol. 2014 Mar 6;426(5):1004-18. doi: 10.1016/j.jmb.2013.06.040. Epub 2013 , Jul 30. PMID:23911548 doi:http://dx.doi.org/10.1016/j.jmb.2013.06.040
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OCA