2k46

Xenopus laevis malectin complexed with nigerose (Glcalpha1-3Glc)Xenopus laevis malectin complexed with nigerose (Glcalpha1-3Glc)

Structural highlights

2k46 is a 1 chain structure with sequence from Xenopus laevis. Full experimental information is available from OCA. For a guided tour on the structure components use FirstGlance.
Method:	Solution NMR
Ligands:	,
Resources:	FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

MLECA_XENLA Carbohydate-binding protein with a strong ligand preference for Glc2-N-glycan. May play a role in the early steps of protein N-glycosylation. Can bind di- or higher oligomers but not monomers of glucose, including maltose, maltotriose, maltotetraose, maltoheptaose, nigerose, kojibose, cellobiose and isomaltose, although based on their subcellular locations, these are unlikely to all be physiological ligands.^[1]

Evolutionary Conservation

Check, as determined by ConSurfDB. You may read the explanation of the method and the full data available from ConSurf.

References

↑ Schallus T, Jaeckh C, Feher K, Palma AS, Liu Y, Simpson JC, Mackeen M, Stier G, Gibson TJ, Feizi T, Pieler T, Muhle-Goll C. Malectin: a novel carbohydrate-binding protein of the endoplasmic reticulum and a candidate player in the early steps of protein N-glycosylation. Mol Biol Cell. 2008 Aug;19(8):3404-14. Epub 2008 Jun 4. PMID:18524852 doi:10.1091/mbc.E08-04-0354

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OCA

[1] Schallus T, Jaeckh C, Feher K, Palma AS, Liu Y, Simpson JC, Mackeen M, Stier G, Gibson TJ, Feizi T, Pieler T, Muhle-Goll C. Malectin: a novel carbohydrate-binding protein of the endoplasmic reticulum and a candidate player in the early steps of protein N-glycosylation. Mol Biol Cell. 2008 Aug;19(8):3404-14. Epub 2008 Jun 4. PMID:18524852 doi:10.1091/mbc.E08-04-0354

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2k46

Xenopus laevis malectin complexed with nigerose (Glcalpha1-3Glc)Xenopus laevis malectin complexed with nigerose (Glcalpha1-3Glc)

Structural highlights

Function

Evolutionary Conservation

References

Contents

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2k46

Xenopus laevis malectin complexed with nigerose (Glcalpha1-3Glc)Xenopus laevis malectin complexed with nigerose (Glcalpha1-3Glc)

Structural highlights

Function

Evolutionary Conservation

References

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