2ist

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crystal structure of RluD from E. colicrystal structure of RluD from E. coli

Structural highlights

2ist is a 1 chain structure with sequence from Escherichia coli. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Method:X-ray diffraction, Resolution 1.86Å
Ligands:,
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

RLUD_ECOLI Responsible for synthesis of pseudouridine from uracil at positions 1911, 1915 and 1917 in 23S ribosomal RNA. Isomerization occurs as a late step during the assembly of the large ribosomal subunit.[1] [2]

Evolutionary Conservation

Check, as determined by ConSurfDB. You may read the explanation of the method and the full data available from ConSurf.

See Also

References

  1. ↑ Wrzesinski J, Bakin A, Ofengand J, Lane BG. Isolation and properties of Escherichia coli 23S-RNA pseudouridine 1911, 1915, 1917 synthase (RluD). IUBMB Life. 2000 Jul;50(1):33-7. PMID:11087118 doi:http://dx.doi.org/10.1080/15216540050176566
  2. ↑ Leppik M, Peil L, Kipper K, Liiv A, Remme J. Substrate specificity of the pseudouridine synthase RluD in Escherichia coli. FEBS J. 2007 Nov;274(21):5759-66. Epub 2007 Oct 12. PMID:17937767 doi:http://dx.doi.org/10.1111/j.1742-4658.2007.06101.x

2ist, resolution 1.86Å

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OCA
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