2hi1

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The structure of a putative 4-hydroxythreonine-4-phosphate dehydrogenase from Salmonella typhimurium.The structure of a putative 4-hydroxythreonine-4-phosphate dehydrogenase from Salmonella typhimurium.

Structural highlights

2hi1 is a 2 chain structure with sequence from Salmonella enterica subsp. enterica serovar Typhimurium str. LT2. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Method:X-ray diffraction, Resolution 2.3Å
Ligands:
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT, TOPSAN

Function

PDXA2_SALTY Catalyzes the NAD(P)-dependent oxidation of 4-(phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4-(phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP) (By similarity).[HAMAP-Rule:MF_00536]

Evolutionary Conservation

Check, as determined by ConSurfDB. You may read the explanation of the method and the full data available from ConSurf.

2hi1, resolution 2.30Å

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OCA