2f2c

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X-ray structure of human CDK6-Vcyclinwith the inhibitor aminopurvalanolX-ray structure of human CDK6-Vcyclinwith the inhibitor aminopurvalanol

Structural highlights

2f2c is a 2 chain structure with sequence from Herpesvirus saimiri (strain 11) and Homo sapiens. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Method:X-ray diffraction, Resolution 2.8Å
Ligands:, ,
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

CGH2_SHV21 May be highly relevant to the process of cellular transformation and rapid T-cell proliferation effected by HVS during latent infections of T-cells in susceptible hosts.

Evolutionary Conservation

Check, as determined by ConSurfDB. You may read the explanation of the method and the full data available from ConSurf.

See Also

2f2c, resolution 2.80Å

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OCA