2eqr

Solution structure of the first SANT domain from human nuclear receptor corepressor 1Solution structure of the first SANT domain from human nuclear receptor corepressor 1

Structural highlights

2eqr is a 1 chain structure with sequence from Homo sapiens. Full experimental information is available from OCA. For a guided tour on the structure components use FirstGlance.
Method:	Solution NMR
Resources:	FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT, TOPSAN

Function

NCOR1_HUMAN Mediates transcriptional repression by certain nuclear receptors. Part of a complex which promotes histone deacetylation and the formation of repressive chromatin structures which may impede the access of basal transcription factors.^[1]

Evolutionary Conservation

Check, as determined by ConSurfDB. You may read the explanation of the method and the full data available from ConSurf.

References

↑ Yoon HG, Chan DW, Reynolds AB, Qin J, Wong J. N-CoR mediates DNA methylation-dependent repression through a methyl CpG binding protein Kaiso. Mol Cell. 2003 Sep;12(3):723-34. PMID:14527417

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OCA

[1] Yoon HG, Chan DW, Reynolds AB, Qin J, Wong J. N-CoR mediates DNA methylation-dependent repression through a methyl CpG binding protein Kaiso. Mol Cell. 2003 Sep;12(3):723-34. PMID:14527417

[1]

2eqr

Solution structure of the first SANT domain from human nuclear receptor corepressor 1Solution structure of the first SANT domain from human nuclear receptor corepressor 1

Structural highlights

Function

Evolutionary Conservation

See Also

References

Contents

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2eqr

Solution structure of the first SANT domain from human nuclear receptor corepressor 1Solution structure of the first SANT domain from human nuclear receptor corepressor 1

Structural highlights

Function

Evolutionary Conservation

See Also

References

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