2eqp

From Proteopedia
Jump to navigation Jump to search

Solution structure of the stn_TNFRSF12A_TNFR domain of Tumor necrosis factor receptor superfamily member 12A precursorSolution structure of the stn_TNFRSF12A_TNFR domain of Tumor necrosis factor receptor superfamily member 12A precursor

Structural highlights

2eqp is a 1 chain structure with sequence from Homo sapiens. Full experimental information is available from OCA. For a guided tour on the structure components use FirstGlance.
Method:Solution NMR
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT, TOPSAN

Function

TNR12_HUMAN Receptor for TNFSF12/TWEAK. Weak inducer of apoptosis in some cell types. Promotes angiogenesis and the proliferation of endothelial cells. May modulate cellular adhesion to matrix proteins.[1]

See Also

References

  1. Wiley SR, Cassiano L, Lofton T, Davis-Smith T, Winkles JA, Lindner V, Liu H, Daniel TO, Smith CA, Fanslow WC. A novel TNF receptor family member binds TWEAK and is implicated in angiogenesis. Immunity. 2001 Nov;15(5):837-46. PMID:11728344
Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)Proteopedia Page Contributors and Editors (what is this?)

OCA